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GST-P polyclonal antibody

 
ADI-MSA-101-E 100 µl 258.00 USD
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Product Specification

Alternative Name:GST-π, Glutathione S-transferase P, GSTP1
 
Host:Rabbit
 
Immunogen:Native rat liver GST-P.
 
UniProt ID:P04906
 
Species reactivity:Human, Mouse, Rat
 
Applications:IHC, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (1:1,000-1:2,000)
Western Blot (1:1,000-1:2,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~27kDa by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The GST superfamily of enzymes play an important role in detoxification of xenobiotics by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. There are four main GST classes; alpha, mu, pi, and tau. GST-P is a member of the pi class of GSTs, and its expression is specifically increased in the early stages of rat hepatocarcinogenesis. Due to its high affinity for glutathione, GST is frequently utilized as an approximately 26 kDa fusion tag for the expression and purification of recombinant proteins.
 
MSA-101 WB
Western blot analysis of mouse kidney (1), WR19L (2), PC12 (3) and Jurkat (4) using GST-P pAb.
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MSA-101 WB

Product Literature References

Hexachlorobenzene induces cell proliferation, and aryl hydrocarbon receptor expression (AhR) in rat liver preneoplastic foci, and in the human hepatoma cell line HepG2. AhR is a mediator of ERK1/2 signaling, and cell cycle regulation in HCB-treated HepG2 cells: A.C. de Tomaso Portaz, et al. ; Toxicology 336, 36 (2015), Application(s): Immunohistochemisty , Abstract;

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