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Cytochrome P450 polyclonal antibody

 
ADI-MFO-100-D 50 µg 161.00 USD
 
ADI-MFO-100-F 200 µg 356.00 USD
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Product Specification

Alternative Name:CYPR
 
Host:Rabbit
 
Immunogen:Native rat Cytochrome p450.
 
UniProt ID:P05182
 
GenBank ID:M20131
 
Species reactivity:Human, Mouse, Rat
Clam, Dog, Guinea pig, Horse, Monkey, Rabbit
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~50-55 kDa by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Cytochrome p450 is a highly conserved and diverse family of heme-containing proteins that function in the metabolism of numerous endogenous and exogenous substrates.. The human genome encodes 57 p450 genes divided among 18 families, which together account for the diversity of substrates metabolized. p450 is the primary conjugating enzyme in phase I metabolism and detoxification of endogenous and exogenous compounds, and are primarily localized to the inner membranes of mitochondria and the ER. Eukaryotic microsomal cytochrome p450 enzymes receive electrons from the FAD- and FMN-containing enzyme NADPH:cytochrome p450 reductase (CPR).
 
ADI-MFO-100 WB
Western blot analysis of Cytochrome P450: Lane 1: MWM, Lane 2: Human Liver microsomes, Lane 3: Rat Liver Microsomes, Lane 4: Mouse Liver Microsomes, Lane 5: Rabbit Liver Microsomes.
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ADI-MFO-100 WB

Product Literature References

Effect of exposure to benzo[a]pyrene on SODs, CYP1A1/1A2- and CYP2E1 immunopositive proteins in the blood clam Scapharca inaequivalvis: M. Monari, et al. ; Mar. Environ. Res. 63, 200 (2007), Application(s): WB using clam tissue, Abstract;
Ethanol withdrawal induced CYP2E1 degradation in vivo, blocked by proteasomal inhibitor PS-341: S.W. French, et al. ; Free Radic. Biol. Med. 32, 17 (2002), Application(s): WB using rat samples, Abstract;

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