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PKA (CT) polyclonal antibody

 
ADI-KAS-PK017-D 50 µg 151.00 USD
 
ADI-KAS-PK017-F 200 µg 345.00 USD
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Product Specification

Alternative Name:Protein Kinase A
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to a portion of human PKA.
 
UniProt ID:P17612 (Cα subunit), P22694 (Cβ subunit), P22162 (Cγ subunit), P10644 (RIα subunit), P31321 (RIβ subunit), P13861 (RIIα subunit), P31323 (RIIβ subunit)
 
Species reactivity:Human, Mouse, Rat
Bovine, Dog, Guinea pig, Hamster, Monkey, Porcine, Rabbit, Sheep, Xenopus
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~40kDa by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:PKA (Protein Kinase A), also known as cAMP-dependent protein kinase, phosphorylates serine or threonine residues in target protein in response to elevated levels of cAMP. Inactive PKA exists as a tetrameric protein composed of two regulatory (R) subunits and two catalytic (C) subunits. Activation occurs when two cAMP molecules bind to each R subunit which causes a conformational change that releases the active C subunits.
 
KAS-PK017 WB
Western blot analysis of PKA: Lane 1: MW marker, Lane 2: CHO-K1, Lane 3: Mouse Brain, Lane 4: Rat Brain, Lane 5: HeLa, Lane 6: 3T3, Lane 7: PC-12.
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KAS-PK017 WB

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