| ADI-KAP-TF118-E | 100 µg | 340.00 USD |  |
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| Alternative Name: | IκB kinase |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of human IKKβ. The sequence differs from mouse IKKβ by one amino acid. |
| UniProt ID: | O14920 |
| GenBank ID: | AF029684.1 |
| Species reactivity: | Human |
| Applications: | ICC, WB |
| Recommended Dilutions/Conditions: | Western Blot (2µg/ml, colorimetric) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~87kDa by Western blot. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | Nuclear factor κ B (NF-κB) is a ubiquitous and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-κB is associated with IkappaB proteins in the cell cytoplasm, which inhibit NF-κB activity. IkappaB is phosphorylated by IkappaB kinase (IKK) complex that contains IKKalpha, IKKbeta, and IKKgamma. A molecule in the IKK complex was identified and designated IKKepsilon/IKK-iota. |
