Product Specification
| Alternative Name: | Signal transducer and activator of transcription 1 |
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| Host: | Rabbit |
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| Immunogen: | Synthetic peptide corresponding to a portion of human Stat1 phosphorylated at Ser727. |
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| UniProt ID: | P42224 |
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| Species reactivity: | Human
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| Crossreactivity: | Weakly cross-reacts with mouse, pig, hamster and monkey Stat1. |
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| Applications: | WB
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| Recommended Dilutions/Conditions: | Western Blot (1µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application. |
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| Application Notes: | Detects a band of ~91kDa by Western blot. |
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| Purity Detail: | Peptide affinity purified. |
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| Formulation: | Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Shipped on Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | Stats (Signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, Stats enter the nucleus to regulate transcription of many different genes. |
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Western blot analysis of untreated (1) and IFNalpha-treated (2) HeLa cells probed with Stat1 (pSer727), pAb
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For Research Use Only. Not for use in diagnostic procedures.
