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Phosphoserine polyclonal antibody (HRP conjugate)

 
ADI-KAP-ST2103-E 100 µg 388.00 USD
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Product Specification

Host:Rabbit
 
Immunogen:Phosphoserine conjugated to KLH and phosvitin mixture.
 
Species reactivity:Species independent
 
Applications:ELISA, WB
 
Recommended Dilutions/Conditions:ELISA (0.5µg/ml)
Western Blot (2µg/ml, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Immunoaffinity purified.
 
Formulation:Liquid. In HRP stabilization buffer.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Protein phosphorylation is a complex biochemical process that is regulated by protein kinases that catalyze the transfer of the gamma-P of ATP to a recipient protein that acts as a substrate. This post-translational modification is primarily directed onto serine, threonine, and tyrosine amino acid residues within a protein. Changes in the phosphorylation status of phosphoproteins can alter their biological function, and aberrations in signal transduction cascades have been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders.
 
Phosphoserine polyclonal antibody (HRP conjugate) Western blot
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Phosphoserine polyclonal antibody (HRP conjugate) Western blot

Product Literature References

Fas Ligand-Fas Signaling Participates in Light-Induced Apoptotic Death in Photoreceptor Cells: Q. Chang, et al.; Invest. Ophthalmol. Vis. Sci. 53, 3703 (2012), Application(s): Western Blotting, Abstract; Full Text
PP2A inactivation is a crucial step in triggering apoptin-induced tumor-selective cell killing: R. Zimmerman, et al.; Cell Death Dis. 3, e291 (2012), Application(s): Western Blotting, Abstract; Full Text

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