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Phosphoserine polyclonal antibody

 
ADI-KAP-ST210-E 100 µg 316.00 USD
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Product Specification

Host:Rabbit
 
Immunogen:Phosphoserine conjugated to KLH.
 
Species reactivity:Species independent
 
Applications:ELISA, IHC, IP, WB
 
Recommended Dilutions/Conditions:ELISA (1µg/ml)
Immunohistochemistry (5µg/ml)
Immunoprecipitation (10µg/mg protein)
Western Blot (1µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Peptide affinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol and 0.01% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Protein phosphorylation is a complex biochemical process that is regulated by protein kinases that catalyze the transfer of the gamma-P of ATP to a recipient protein that acts as a substrate. This post-translational modification is primarily directed onto serine, threonine, and tyrosine amino acid residues within a protein. Changes in the phosphorylation status of phosphoproteins can alter their biological function, and aberrations in signal transduction cascades have been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders.
 
Phosphoserine polyclonal antibody Western blot
Western blot analysis of human MMRU melanoma cells probed with Phosphoserine, pAb. Top (from the left): MMRU cells treated with 0 (A), 50 (B), 200 (C), 400 (D) l long wavelength UV, or 0.1µM of okadaic acid (E). Bottom: Same samples probed with β-actin antibody (control).
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Phosphoserine polyclonal antibody Western blot

Product Literature References

Genistein-induced apoptosis and autophagocytosis in ovarian cancer cells: J. Liu, et al. ; Gynecol. Oncol. 105, 23 (2007), Application(s): WB, IP using xenopus tissue, Abstract;

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