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Phosphoserine polyclonal antibody

 
ADI-KAP-ST210-E 100 µg 301.00 USD
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Product Specification

Host:Rabbit
 
Immunogen:Phosphoserine conjugated to KLH.
 
Species reactivity:Species independent
 
Applications:ELISA, IHC, IP, WB
 
Recommended Dilutions/Conditions:ELISA (1µg/ml)
Immunohistochemistry (5µg/ml)
Immunoprecipitation (10µg/mg protein)
Western Blot (1µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Peptide affinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol and 0.01% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Protein phosphorylation is a complex biochemical process that is regulated by protein kinases that catalyze the transfer of the gamma-P of ATP to a recipient protein that acts as a substrate. This post-translational modification is primarily directed onto serine, threonine, and tyrosine amino acid residues within a protein. Changes in the phosphorylation status of phosphoproteins can alter their biological function, and aberrations in signal transduction cascades have been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders.
 
KAP-ST210 WB
Western blot analysis of human MMRU melanoma cells probed with Phosphoserine, pAb. Top (from the left): MMRU cells treated with 0 (A), 50 (B), 200 (C), 400 (D) l long wavelength UV, or 0.1µM of okadaic acid (E). Bottom: Same samples probed with β-actin antibody (control).
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KAP-ST210 WB

Product Literature References

Genistein-induced apoptosis and autophagocytosis in ovarian cancer cells: J. Liu, et al. ; Gynecol. Oncol. 105, 23 (2007), Application(s): WB, IP using xenopus tissue, Abstract;

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