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PKC polyclonal antibody

 
ADI-KAP-PK003-E 100 µg 276.00 USD
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Product Specification

Alternative Name:protein kinase C
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to a portion of human PKC. The sequence is completely conserved between the α, β, and δ isoforms of PKC.
 
UniProt ID:P17252 (PKCalpha)
 
Species reactivity:Human, Mouse, Rat
Bovine, Chicken, Dog, Guinea pig, Monkey, Porcine, Rabbit, Sheep
 
Applications:IHC, IP, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (1:50)
Immunoprecipitation (12.5µg/ml)
Western Blot (2µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~67-83kDa by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In borate buffered saline, pH 8.2.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Protein Kinase C (PKC) is a large superfamily of serine/threonine kinases that mediate essential cellular signals required for activation, proliferation, differentiation and survival. There are at least ten PKC isotypes that are closely related in structure but that have distinct patterns of tissue distribution and function. The PKC isotypes can be subdivided into three classes based on primary structure and biochemical properties. These are: classical or conventional PKC isotypes (cPKC), novel PKC isotypes (nPKC) and atypical PKC isotypes (aPKC).
 
KAP-PK003 WB
Western blot analysis of human thymus HS67 cell lysate, probed with PKC pAb.
KAP-PK003 IHC
Immunohistochemistry analysis of human lung cancer tissue with PKC pAb.
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KAP-PK003 WB KAP-PK003 IHC

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