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PKA (NT) polyclonal antibody

 
ADI-KAP-PK001-D 50 µg 140.00 USD
 
ADI-KAP-PK001-F 200 µg 320.00 USD
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Product Specification

Alternative Name:Protein Kinase A
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to a portion of the 40 kDa isoform of the catalytic subunit of human PKA.
 
UniProt ID:P17612 (Cα subunit), P22694 (Cβ subunit), P22162 (Cγ subunit), P10644 (RIα subunit), P31321 (RIβ subunit), P13861 (RIIα subunit), P31323 (RIIβ subunit)
 
Species reactivity:Human, Mouse, Rat
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~40kDa by Western blot.
 
Purity Detail:Immunoaffinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:PKA (Protein Kinase A), also known as cAMP-dependent protein kinase, phosphorylates serine or threonine residues in target protein in response to elevated levels of cAMP. Inactive PKA exists as a tetrameric protein composed of two regulatory (R) subunits and two catalytic (C) subunits. Activation occurs when two cAMP molecules bind to each R subunit which causes a conformational change that releases the active C subunits.
 
KAP-PK001 WB
Western blot analysis of Prod. No. ADI-KAP-PK001: Lane 1: MW marker, Lane 2: Mouse Brain, Lane 3: Rat Brain, and Lane 4: MDBK
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KAP-PK001 WB

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