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Rap1 polyclonal antibody

ADI-KAP-GP125-C 25 µg 132.00 USD
ADI-KAP-GP125-E 100 µg 287.00 USD
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Product Specification

Alternative Name:KREV1
Immunogen:Synthetic peptide corresponding to a portion of human Rap1a. The sequence is completely conserved in mouse, rat, bovine, chicken, Xenopus. Differs from a portion of Rap1b by 2 amino acids.
UniProt ID:P62834 (Rap1A), P61224 (Rap1B)
GenBank ID:A08691
Species reactivity:Human, Mouse, Rat
Bovine, Chicken, Dog, Guinea pig, Hamster, Monkey, Porcine, Rabbit, Sheep, Xenopus
Recommended Dilutions/Conditions:Western Blot (1µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~25kDa by Western blot.
Purity Detail:Peptide affinity purified.
Formulation:Liquid. In PBS.
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:Rap1, which is a member of the Ras family of GTP-binding proteins, cycles between an active GTP-bound and an unactive GDP-bound form that is mediated by GTPase activating protein (GAP). Rap1 is proposed to regulate Ras-mediated signaling and may also be involved in the regulation of Integrin-mediated cell adhesion although the mechanism of regulation is not known.

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