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RAB3A polyclonal antibody

ADI-KAP-GP003-C 25 µg 132.00 USD
ADI-KAP-GP003-E 100 µg 263.00 USD
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Product Specification

Alternative Name:Ras-related protein Rab-3A
Immunogen:Synthetic peptide corresponding to a portion of human Rab3A.
UniProt ID:P20336
Species reactivity:Mouse, Rat
Applications:IHC (PS), WB
Recommended Dilutions/Conditions:Western Blot (1µg/ml, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~25kDa by Western blot.
Purity Detail:Peptide immunoaffinity purified.
Formulation:Liquid. In borate buffered saline, pH 8.2, containing 25mM sodium borate, 100mM boric acid, 75mM sodium chloride, and 5mM EDTA.
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:The Rab family of GTP-binding proteins are members of the Ras superfamily of small G proteins, and participate in multiple steps of the membrane trafficking. Rab3A participates in the fusion of synaptic vesicles during neurotransmitter release, a process regulated by GDP/GDP exchange cofactors such as GAP, GDI, GRF, and rabphilin. Rab4 regulates recycling of proteins from the early endosome to the surface of many cell types, regulating glucose transporter and transferrin receptor cell surface localization. Rab5 regulates the fusion of plasma membrane-derived clathrin-coated vesicles with early endosomes and homotypic fusion among early endosomes.
Immunohistochemistry analysis of human brain, cortex tissue stained with RAB3A, pAb at 10µg/ml.
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Product Literature References

Rab3A, a possible marker of cortical granules, participates in cortical granule exocytosis in mouse eggs: O.D. Bello, et al.; Exp. Cell. Res. 4827, 30183 (2016), Application(s): ICC, Immunoblotting, Abstract;

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