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[pThr232]Aurora B polyclonal antibody

 
ADI-KAP-CC203-D 50 µg 215.00 USD
 
ADI-KAP-CC203-F 200 µg 399.00 USD
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Product Specification

Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to a portion of human Aurora B phosphorylated at Thr232.
 
UniProt ID:Q96GD4
 
GenBank ID:AAH80581
 
Species reactivity:Human
 
Crossreactivity:Weakly cross-reacts with mouse, rat, bovine and pig Aurora B.
 
Applications:IHC (PS), WB
 
Recommended Dilutions/Conditions:Western Blot (1µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Peptide affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Aurora A, B, and C have emerged as key mitotic regulators of mammalian centrosome function, chromosome segregation and cytokinesis. Aurora B is one of several chromosomal passenger proteins involved in chromosome alignment at the metaphase plate and cytokinesis. Phosphorylation of a threonine residue in the Aurora activation loop (Thr232 in human Aurora B) is believed to be an essential regulatory mechanism in Aurora kinase activation.
 
ADI-KAP-CC203 IHC1
IHC Analysis: Human adrenal tissue stained with [pThr232]Aurora B, pAb at 5µg/ml.
ADI-KAP-CC203 IHC2
IHC Analysis: Human skin tissue stained with [pThr232]Aurora B, pAb at 5µg/ml.
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ADI-KAP-CC203 IHC1 ADI-KAP-CC203 IHC2

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Aurora kinase
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