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[pTyr15]Cdk1/cdc2 polyclonal antibody

 
ADI-KAP-CC015-E 100 µl 345.00 USD
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Product Specification

Alternative Name:Cell division cycle 2, Cyclin-dependent kinase 1
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to a portion of human Cdk1/cdc2 phosphorylated at Tyr1173. The sequence is completely conserved in mouse, rat, Drosophila and Xenopus.
 
UniProt ID:P06493
 
Species reactivity:Human, Mouse, Rat
Xenopus
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Peptide affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The cell division cycle (cdc) group of proteins consists of many protein classes, including cyclin dependent kinases (Cdks), phosphoprotein phosphatases, mitogen activated kinases, small GTPases, and cyclins. These proteins play a central role in regulating progression through the cell cycle through the formation and/or modification of key substrates. Cdc42 belongs to the Rho-family of GTPases, and promotes actin polymerization to form filopodia. Cdc25A is a dual-specificity phosphatase that acts on phosphorylated threonine and tyrosine residues of Cdks, leading to binding and activation of their partner cyclins.
 
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