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FAK monoclonal antibody (12G4)

 
ADI-KAM-TK050-E 100 µg 313.00 USD
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Product Specification

Alternative Name:Focal adhesion kinase
 
Clone:12G4
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human FAK.
 
UniProt ID:Q05397
 
Species reactivity:Human, Mouse, Rat
 
Applications:ICC, IP, WB
 
Recommended Dilutions/Conditions:Immunocytochemistry (10µg/ml)
Immunoprecipitation (2µg/500µl from 5x106cells)
Western Blot (1µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~125kDa by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:FAK, Focal adhesion kinase, is a 125 kDa non-receptor protein tyrosine kinase that is a substrate for Src and a key element in growth factor and integrin signaling. FAK plays a central role in cell spreading, differentiation, migration, cell death, and acceleration of the G1 to S phase transition of the cell cycle.
 

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