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CREB monoclonal antibody (82B514)

 
ADI-KAM-TF030-E 100 µg 240.00 USD
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Product Specification

Alternative Name:cAMP responsive element binding protein
 
Clone:82B514
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Synthetic peptide corresponding to a portion of human CREB.
 
UniProt ID:P16220
 
Species reactivity:Human
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (2-4µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS containing 0.2% gelatin and 0.05% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The transcription factor CREB (cAMP response element binding) binds the palindromic octanucleotide TGACGTCA. Members of the ATF/CREB family include CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2, and ATF-3. Phosphorylation of CREB allows recruitment of CREB-binding protein (CBP), a large co-activator that contacts the general transcriptional machinery. CREB-mediated transcription regulates diverse cellular responses, including intermediary metabolism, neuronal signaling, cell proliferation, and apoptosis.
 
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