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RanGEF monoclonal antibody (3D11)

 
ADI-KAM-CC225-E 100 µg 296.00 USD
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Product Specification

Alternative Name:RCC1
 
Clone:3D11
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant human RanGEF.
 
UniProt ID:P18754
 
Species reactivity:Human, Mouse, Rat
 
Applications:ICC, IP, WB
 
Recommended Dilutions/Conditions:Immunocytochemistry (5µg/ml)
Immunoprecipitation (2µg/ml)
Western Blot (1µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~45kDa by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Lyophilized. In PBS, pH 7.2, containing 1% sucrose. No preservatives. For a stock solution of 1.0mg/ml, reconstitute with 100mg/ml of sterile distilled water.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:RanGEF, also known as regulator of chromosome condensation (RCC1), is an abundant, highly conserved chromatin-associated 45 kDa protein. RanGEF is involved in the regulation of the onset of chromosome condensation in the S phase, and is the principle mammalian guanine nucleotide exchange factor (GEF) for the nuclear G protein Ran. RanGEF plays important roles in RNA transcription and processing, DNA replication, nuclear pore transport function, and cell cycle regulation.
 
RanGEF monoclonal antibody (3D11) Western blot
Western blot analysis of RanGEF probed with RanGEF (RCC1), mAb (3D11).
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RanGEF monoclonal antibody (3D11) Western blot

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