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RanGEF monoclonal antibody (3D11)

 
ADI-KAM-CC225-E 100 µg 269.00 USD
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Product Specification

Alternative Name:RCC1
 
Clone:3D11
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant human RanGEF.
 
UniProt ID:P18754
 
Species reactivity:Human, Mouse, Rat
 
Applications:ICC, IP, WB
 
Recommended Dilutions/Conditions:Immunocytochemistry (5µg/ml)
Immunoprecipitation (2µg/ml)
Western Blot (1µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~45kDa by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Lyophilized. In PBS, pH 7.2, containing 1% sucrose. No preservatives. For a stock solution of 1.0mg/ml, reconstitute with 100mg/ml of sterile distilled water.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:RanGEF, also known as regulator of chromosome condensation (RCC1), is an abundant, highly conserved chromatin-associated 45 kDa protein. RanGEF is involved in the regulation of the onset of chromosome condensation in the S phase, and is the principle mammalian guanine nucleotide exchange factor (GEF) for the nuclear G protein Ran. RanGEF plays important roles in RNA transcription and processing, DNA replication, nuclear pore transport function, and cell cycle regulation.
 
KAM-CC225 WB
Western blot analysis of RanGEF probed with RanGEF (RCC1), mAb (3D11).
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KAM-CC225 WB

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