| ADI-KAM-CC225-E | 100 µg | 274.00 USD |  |
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| Alternative Name: | RCC1 |
| Clone: | 3D11 |
| Host: | Mouse |
| Isotype: | IgG1 |
| Immunogen: | Recombinant human RanGEF. |
| UniProt ID: | P18754 |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | ICC, IP, WB |
| Recommended Dilutions/Conditions: | Immunocytochemistry (5µg/ml) Immunoprecipitation (2µg/ml) Western Blot (1µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~45kDa by Western blot. |
| Purity Detail: | Protein A affinity purified. |
| Formulation: | Lyophilized. In PBS, pH 7.2, containing 1% sucrose. No preservatives. For a stock solution of 1.0mg/ml, reconstitute with 100mg/ml of sterile distilled water. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | RanGEF, also known as regulator of chromosome condensation (RCC1), is an abundant, highly conserved chromatin-associated 45 kDa protein. RanGEF is involved in the regulation of the onset of chromosome condensation in the S phase, and is the principle mammalian guanine nucleotide exchange factor (GEF) for the nuclear G protein Ran. RanGEF plays important roles in RNA transcription and processing, DNA replication, nuclear pore transport function, and cell cycle regulation. |
A431, (cell lysate) |
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| Human, WB | Print as PDF | ||||||
| ADI-LYC-A4100-F | 200 µg | 110.00 USD | |
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HeLa, (cell lysate) |
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| Human, WB | Print as PDF | ||||||
| ADI-LYC-HL100-F | 200 µg | 111.00 USD | |
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Jurkat, (cell lysate) |
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| Human, WB | Print as PDF | ||||||
| ADI-LYC-JK100-F | 200 µg | 111.00 USD | |
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PC-12, (cell lysate) |
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| Rat, WB | Print as PDF | ||||||
| ADI-LYC-PC100-F | 200 µg | 111.00 USD | |
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Goat anti-mouse IgG F(ab')2, polyclonal antibody (HRP conjugate) |
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| ELISA, IHC, WB | Print as PDF | ||||||
| ADI-SAB-100-J | 1 ml | 120.00 USD | |
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