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Cyclin D3 monoclonal antibody (DCS-22)

 
ADI-KAM-CC203-F 200 µl 250.00 USD
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Product Specification

Alternative Name:CCND3
 
Clone:DCS-22
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant human Cyclin D3.
 
UniProt ID:P30281
 
Species reactivity:Human
 
Applications:IHC, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (1:20-1:40)
Western Blot (1:100-1:200, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Formulation:Liquid. In concentrated mouse immunoglobulin containing 0.1% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:Cyclins are a family of proteins which function as the regulatory subunits of cyclin/cyclin-dependent kinase (Cdk) holoenzymes, mediating entry into and progression through the cell cycle. Each cyclin is expressed in a temporal fashion during the cell cycle, partnering with a specific Cdk to activate its protein kinase activity. The most well defined mitotic cyclins are: cyclin D, which partners with cdks 4 and 6 during early G1 phase; cyclin E, which activates Cdk2 in the G1 to S phase transition; cyclin A, which utilizes Cdks 1 and 2 during progression through S phase and into G2; and cyclin B, which activates Cdk1 in M-phase promotion.
 

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