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Cullin 1 monoclonal antibody (AS97.1)

 
ADI-KAM-CC135-D 50 µg 194.00 USD
 
ADI-KAM-CC135-F 200 µg 378.00 USD
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Product Specification

Alternative Name:CUL1
 
Clone:AS97.1
 
Host:Mouse
 
Isotype:IgG2a
 
Immunogen:Recombinant human cullin 1.
 
UniProt ID:Q13616
 
Species reactivity:Human, Mouse, Rat
Bovine, Monkey, Rabbit
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1:250, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~93kDa by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 0.1mM PMSF and 50% glycerol.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The human Cullin family of genes consists of Cul-1, Cul-2, Cul-3, Cul-4a, Cul-4b, and Cul-5. Among the 6 members, Cul-1 and Cul-2 are very well characterized. Cul-2 is homologous to the Saccharomyces cerevisiae cdc53 gene. Studies have shown that Cul-1 forms an E3 ubiquitin-ligase, called the SCF complex (Skp1 and F-box protein such as bTrCp or FWD1), which controls the proteolysis of G1 cell cycle regulatory proteins.
 

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