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Cdc25A monoclonal antibody (DCS-120)

 
ADI-KAM-CC085-E 100 µg 248.00 USD
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Product Specification

Alternative Name:Cell division cycle 25A
 
Clone:DCS-120
 
Host:Mouse
 
Isotype:IgG2a
 
Immunogen:Recombinant human cdc25A.
 
UniProt ID:P30304
 
GenBank ID:AY137580
 
Gene/Protein Identifier:NM_001789 (RefSeq)
 
Species reactivity:Human, Mouse, Rat
 
Applications:IP, WB
 
Recommended Dilutions/Conditions:Immunoprecipitation (3µg/200-300µl)
Western Blot (1-5µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The cell division cycle (cdc) group of proteins consists of many protein classes, including cyclin dependent kinases (Cdks), phosphoprotein phosphatases, mitogen activated kinases, small GTPases, and cyclins. These proteins play a central role in regulating progression through the cell cycle through the formation and/or modification of key substrates. Cdc42 belongs to the Rho-family of GTPases, and promotes actin polymerization to form filopodia. Cdc25A is a dual-specificity phosphatase that acts on phosphorylated threonine and tyrosine residues of Cdks, leading to binding and activation of their partner cyclins.
 
KAM-CC085-Antibody-Blot
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KAM-CC085-Antibody-Blot

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