14-3-3 β, mAb (4E1)

Alternative Name:	Protein kinase C inhibitor protein, Protein 1054

Purity Detail:	Protein A affinity purified.

Formulation:	Lyophilized. In PBS, pH 7.4, containing 10mg/ml sucrose and 1mg/ml sodium azide. For a stock solution of 1.0mg/ml reconstitute with 100μl of sterile distilled water.

Clone:	4E1

Isotype:	Mouse IgG2b

Immunogen:	Recombinant rat 14-3-3 β.

Specificity:	Recognizes mouse and rat 14-3-3 β.

Application:	Immunoprecipitation (5-10µg/ml) Western Blot (1-5µg/ml, colorimetric) Optimal conditions must be determined individually for each application.

Long Term Storage:	-20°C

Miscellaneous/General:	14-3-3 proteins are highly conserved proteins that play a role in both signal transduction and progression through the cell cycle by binding to and regulating a number of different proteins. 14-3-3 proteins activate tyrosine and tryptophan hydroxylases and protein kinase C. They mediate signal transduction by binding to phosphoserine-containing proteins. There are at least 7 mammalian isoforms.