14-3-3 β/ε/ζ, mAb (3C8)

Alternative Name:	Protein kinase C inhibitor protein, Protein 1054

Purity Detail:	Protein A affinity purified.

Formulation:	Liquid. In PBS, pH 7.2, containing 1% sucrose and 0.1% sodium azide.

Clone:	3C8

Isotype:	Mouse IgG2b

Immunogen:	Recombinant human 14-3-3 β.

Specificity:	Recognizes human, mouse and rat 14-3-3 β/ε/ζ.

Application:	Western Blot (1-10µg/ml, ECL) Optimal conditions must be determined individually for each application.

Long Term Storage:	-20°C

Miscellaneous/General:	14-3-3 proteins are highly conserved proteins that play a role in both signal transduction and progression through the cell cycle by binding to and regulating a number of different proteins. 14-3-3 proteins activate tyrosine and tryptophan hydroxylases and protein kinase C. They mediate signal transduction by binding to phosphoserine-containing proteins. There are at least 7 mammalian isoforms.