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TLR4 polyclonal antibody

ADI-CSA-801-E 100 µg 281.00 USD
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Product Specification

Alternative Name:Toll-like receptor 4
Immunogen:Synthetic peptide corresponding to a portion of mouse TLR4.
UniProt ID:Q9QUK6, Q8K2T5
GenBank ID:AAH29856
Species reactivity:Mouse
Applications:ICC, IHC (PS), WB
Recommended Dilutions/Conditions:Immunocytochemistry (1:10)
Immunohistochemistry (1:50, paraffin)
Western Blot (1-3µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~90kDa by Western blot.
Purity Detail:Protein G affinity purified.
Formulation:Liquid. In PBS containing 0.05% BSA and 0.5% sodium azide.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:The TLRs (Toll-like receptors) are a group of evolutionarily conserved pattern recognition molecules that play a key role in host defense during microbial infection by regulating both innate and adaptive immune responses. TLRs are type I transmembrane proteins with ectodomains containing interspersed leucine-rich repeat (LRR) motifs that are involved in the recognition of various microbial ligands.
CSA-801 WB
Western blot analysis of recombinant mouse TLR4, protein, probed with TLR4 pAb.
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CSA-801 WB

Product Literature References

Fenofibrate improves high-fat diet-induced and palmitate-induced endoplasmic reticulum stress and inflammation in skeletal muscle: F. Dai, et al.; Life Sci. 157, 158 (2016), Application(s): Western blot, Abstract;

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