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HMGB1 monoclonal antibody (KS1)

 
ADI-CSA-614-E 100 µg 301.00 USD
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Product Specification

Alternative Name:SBP-1, High-mobility group box 1
 
Clone:KS1
 
Host:Mouse
 
Isotype:IgG2a
 
Immunogen:Pig HMGB1 (HMG1).
 
UniProt ID:P12682
 
Species reactivity:Human, Mouse, Rat
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (5µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~29kDa by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The chromatin non-histone high mobility group of proteins (HMG)-1 and -2 contain conserved domains known as HMG-boxes. Both HMG-1 and HMG-2 contain an N-terminal HMG box, a central HMG box and an acidic carboxy terminus. HMG-1/2 have been shown to facilitate the binding of various sequence-specific transcription factors to their respective DNA binding sites, such as steroid hormone receptors, and p53.
 

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