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SARM polyclonal antibody

 
ADI-CSA-509-E 100 µg 356.00 USD
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Product Specification

Alternative Name:TIR-1, Sterile α and TIR motif-containing protein 1, SAM and ARM-containing protein, Sterile α motif and armadillo repeat-containing protein
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human SARM.
 
UniProt ID:Q6SZW1
 
Gene/Protein Identifier:NP_055892 (RefSeq)
 
Species reactivity:Human, Mouse
 
Applications:ICC, WB
 
Recommended Dilutions/Conditions:Immunocytochemistry (2µg/ml)
Western Blot (0.5-2.0µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Ion exchange purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:SARM (SAM and ARM-containing protein) is thought to serve as an adaptor protein for the Toll-like receptors (TLRs) and allow for the activation of downstream kinases and NF-κB, ultimately leading to the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interleukin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.
 
CSA-509 WB
Western blot analysis of SARM in Daudi cell lysates with SARM antibody at (A) 0.5, (B) 1, and (C) 2µg/ml.
CSA-509 ICC
Immunocytochemistry analysis of Daudi cells using SARM antibody at 2µg/ml.
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CSA-509 WB CSA-509 ICC

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