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CIKS (Act1) polyclonal antibody

ADI-CSA-507-E 100 µg 363.00 USD
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Product Specification

Immunogen:Synthetic peptide corresponding to the sequence near the N-terminus of human CIKS.
UniProt ID:O43734
Species reactivity:Human
Applications:IHC, WB
Recommended Dilutions/Conditions:Immunohistochemistry (5µg/ml)
Western Blot (0.5-1.0µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~63kDa by Western blot.
Purity Detail:Peptide affinity purified.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Shipping:Blue Ice Not Frozen
Long Term Storage:+4°C
Scientific Background:NF-κB is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB associates with IkappaB proteins in the cell cytoplasm, which inhibit its activity. IkappaB is phosphorylated by IkappaB kinase (IKK) complex that contains IKKalpha, IKKbeta, and IKKgamma. CIKS (connection to IKK and SAPK/Jnk) or Act1 (NF-κB activator) associates with and activates IKK. CIKS/Act1 also activates the activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (Jnk).
CSA-507 WB
Western blot analysis of CIKS expression in human lung (lane A) and placenta (lane B) tissue lysates with CIKS antibody at 1µg /ml.
Immunohistochemistry analysis of CIKS in human lung tissue with CIKS antibody at 5µg/ml.
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CSA-507 WB CSA-507 IHC

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