Actin, pAb



ADI-CSA-400-D	50 µg	130.00 USD

ADI-CSA-400-F	200 µg	310.00 USD

Product Specification

Alternative Name:	ACTA, ACTSA

Purity Detail:	Protein A affinity purified.

Formulation:	Liquid. In PBS, pH 7.2, containing 0.09% sodium azide and 50% glycerol.

Immunogen:	Bovine skeletal muscle Actin.

Source/Host:	From rabbit.

Specificity:	Recognizes human, mouse, rat, bovine, dog, chicken, guinea pig, hamster, monkey, pig, rabbit, sheep and Xenopus Actin. Detects a band of ~42kDa by Western blot.

Application:	Western Blot (1:1000, ECL) Optimal conditions must be determined individually for each application.

Long Term Storage:	-20°C

Miscellaneous/General:	Actin is one of the major proteins (~42 kDa) of the cytoskeleton. It regulates contractile potential in muscle tissues and helps to control the shape as well as the motility of non-muscle cells. Actin is expressed in all eukaryotic cells which makes it a useful loading control in Western blotting experiments. In higher eukaryotes, there are six isoforms of actin: Three alpha-actins (α-skeletal, α-cardiac, α-smooth muscle), one β-actin (β-non-muscle) and two γ-actins (γ-smooth muscle and γ-non-muscle). Actin isoforms show >90% overall sequence homology.

Western Blot Analysis of Actin pAb: Lane 1: MWM, Lane 2: Mouse Heart Tissue Extract, Lane 3: Chicken Heart Tissue Extract.

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Product Literature References

Chemical and biological approaches synergize to ameliorate protein-folding diseases: T.W. Mu, et al. ; Cell 134, 769 (2008), Application(s): WB using human cell lysates, Abstract;