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CD74 monoclonal antibody (PIN.1)

 
ADI-CSA-170-C 25 µg 129.00 USD
 
ADI-CSA-170-E 100 µg 269.00 USD
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Product Specification

Clone:PIN.1
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Synthetic peptide corresponding to a portion of human CD74 invariant chain.
 
UniProt ID:P04233
 
GenBank ID:K01144
 
Species reactivity:Human
 
Applications:Flow Cytometry, ICC, IP, WB
 
Recommended Dilutions/Conditions:Immunoprecipitation (12µg/ml)
Western Blot (1µg/ml colorimetric, 1µg/ml ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The cluster of differentiation (CD) proteins are a group of surface molecules so named for their use in the identification and classification of leukocytes. The structure and function of CD proteins varies greatly and includes a multitude of receptors involved in cell adhesion, signal transduction, and antigen recognition. For example, CD8 (cytotoxic) and CD8 (helper) are well established T-lymphocyte markers, and function as co-receptors for MHC-I and MHC-II, respectively.
 
CSA-170-Antibody-Blot
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CSA-170-Antibody-Blot

Product Literature References

Assembly and intracellular transport of HLA-DM and correction of the class II antigen-processing defect in T2 cells: P. Cresswell, et al. ; Immunity 1, 595 (1994), Application(s): ICC using human samples, Abstract;

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