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COX-1 monoclonal antibody (AS70)

 
ADI-COX-010-E 100 µg 290.00 USD
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Product Specification

Alternative Name:Cyclooxygenase 1, Prostaglandin H synthase 1
 
Clone:AS70
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant human COX-1 (cyclooxygenase-1).
 
UniProt ID:P23219
 
Species reactivity:Human
 
Applications:ELISA
 
Purity Detail:Purified.
 
Formulation:Liquid. In PBS containing 0.08% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Cyclooxygenases-1 and 2 (COX-1 and COX-2) also known as Prostaglandin endoperoxide H synthases-1 and 2 are integral membrane proteins which catalyze the first step of Prostaglandin, Thromboxane, and Procastacyclin production from Arachidonic acid. The COX-1 and COX-2 enzymes are important pharmacologically as targets of nonsteroidal anti-inflammatory drugs (NSAIDs) including aspirin, ibuprofen and the COX-2 inhibitors. Inhibition of Cyclooxygenases with NSAIDs acutely reduces inflammation, pain, and fever.
 

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