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Agrin monoclonal antibody (Agr-33)

 
ADI-AGR-510-D 50 µg 203.00 USD
 
ADI-AGR-510-F 200 µg 378.00 USD
 
ADI-AGR-510-J 1 mg 1,576.00 USD
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Product Specification

Clone:Agr-33
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant rat agrin (C-terminal fragment).
 
UniProt ID:P25304
 
GenBank ID:M64780
 
Species reactivity:Mouse, Rat
 
Applications:ICC, IHC, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (10µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins at the neuromuscular junction during development. Agrin, MuSK, and Rapsyn are all essential components for AChR aggregation, through an unknown mechanism. The C-terminal region of agrin is released into the medium, interacts with receptors on the muscle surface and induces AChR aggregation.
 
AGR-510 IHC
Immunohistochemistry analysis of rat skeletal muscle probed with Agrin, mAb (Agr-33) at 1:100.
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AGR-510 IHC

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