Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Bax polyclonal antibody

 
ADI-AAS-040-D 50 µg 151.00 USD
 
ADI-AAS-040-F 200 µg 356.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:BCL2L4, BCL2-associated X protein
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to a portion of human Bax.
 
UniProt ID:Q07812
 
GenBank ID:L22473
 
Species reactivity:Human, Mouse, Rat
Bovine, Monkey, Porcine, Rabbit
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~22kDa by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Bax is an appromimately 22 kDa pro-apoptotic protein belonging to the Bcl-2 family of proteins, which are characterized by the presence of at least one Bcl-2 homology (BH) domains. Bax normally resides in the cytoplasm, but following an apoptotic stimuli, Bax undergoes a conformational change and translocates to mitochondrial membranes where it inserts and mediates the release of cytochrome c. This activates caspase-3 and perpetuates the apoptotic cascade.
 

Product Literature References

let-7b suppresses apoptosis and autophagy of human mesenchymal stem cells transplanted into ischemia/reperfusion injured heart 7by targeting caspase-3: O. Ham, et al.; Stem Cell Res. Ther. 6, 147 (2015), Application(s): Western blot, Abstract; Full Text
Retinoprotective Effects of Bilberry Anthocyanins via Antioxidant, Anti-Inflammatory, and Anti-Apoptotic Mechanisms in a Visible Light-Induced Retinal Degeneration Model in Pigmented Rabbits: Y. Wang, et al. ; Molecules 20, 22395 (2015), Application(s): Western blot, Abstract; Full Text
Synergistic effect of hyperbaric oxygen preconditioning and hydrogen-rich saline in ameliorating rat flap ischemia/reperfusion injury: Y. Xiao, et al.; Plast. Aesthet. Res. 2, 332 (2015), Application(s): Western blot, Full Text

Related Products

HeLa, (cell lysate) 

Human, WB | Print as PDF
 
ADI-LYC-HL100-F 200 µg 109.00 USD
Do you need bulk/larger quantities?
 

Goat anti-rabbit IgG, polyclonal antibody (HRP conjugate) 

ELISA, IHC, WB | Print as PDF
 
ADI-SAB-300-J 1 ml 118.00 USD
Do you need bulk/larger quantities?
 

Goat anti-rabbit IgG, polyclonal antibody (AP conjugate) 

ELISA, WB | Print as PDF
 
ADI-SAB-301-J 1 ml 129.00 USD
Do you need bulk/larger quantities?
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
Bax
By biological activity:
Bax Polyclonal antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,