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TRAIL (human) polyclonal antibody

 
ADI-AAP-470-E 100 µg 366.00 USD
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Product Specification

Alternative Name:Apo-2L, TNFSF 10, CD253
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human TRAIL.
 
UniProt ID:P50591
 
GenBank ID:U57059
 
Gene/Protein Identifier:8743 (Entrez GeneID)
 
Species reactivity:Human
 
Applications:IHC, WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (20µg/ml)
Western Blot (1µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects bands of ~32kDa and ~24kDa (membrane and soluble forms) by Western blot.
 
Purity Detail:Ion exchange purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Shipping:Blue Ice Not Frozen
 
Long Term Storage:+4°C
 
Scientific Background:TRAIL is a type II membrane protein and expressed in a variety of human tissues. Two death domain containing receptors, DR4 and DR5, have been identified as the receptors for TRAIL. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-κB activation in many tissues and cells.
 
AAP-470 WB
Western blot analysis of TRAIL in HeLa cell lysate containing 10, 2.5, or 1 ng of recombinant protein containing extracellular domain of TRAIL with TRAIL antibody at 1µg/ml.
AAP-470 IHC
Immunohistochemistry analysis of TRAIL in human brain tissue with TRAIL antibody at 20µg/ml.
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AAP-470 WB AAP-470 IHC

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