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TRAF6 polyclonal antibody

 
ADI-AAP-426-E 100 µl 281.00 USD
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Product Specification

Alternative Name:TNF receptor-associated factor 6
 
Host:Rabbit
 
Immunogen:Recombinant mouse TRAF6 (N-terminal fragment).
 
UniProt ID:P70196
 
Species reactivity:Mouse
 
Applications:IP, WB
 
Recommended Dilutions/Conditions:Immunoprecipitation (2-4µg/100-500 µl cell extract from 5x106 cells)
Western Blot (1µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~58kDa by Western blot.
 
Purity Detail:Immunoaffinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:TRAF proteins are multifunctional signal adaptors that are involved in the activation of the kinase cascades which activate c-Jun N-terminal kinase, p38 mitogen activated protein kinase, and the transcription factor NF-κB. Members of the TRAF family form homodimers as well as heterodimers, resulting in extensive diversity and specificity to their function in signal transduction pathways.
 
AAP-426 WB
Western blot analysis of L5178Y (1), WR19L (2) and NIH/3T3 (3) cells, probed with TRAF6 pAb.
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AAP-426 WB

Product Literature References

The Nuclear Receptor AhR Controls Bone Homeostasis by Regulating Osteoclast Differentiation via the RANK/c-Fos Signaling Axis: T. Izawa, et al.; J. Immunol. 197, 4639 (2016), Abstract; Full Text

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