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TRAF6 polyclonal antibody

 
ADI-AAP-426-E 100 µl 296.00 USD
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Product Specification

Alternative Name:TNF receptor-associated factor 6
 
Host:Rabbit
 
Immunogen:Recombinant mouse TRAF6 (N-terminal fragment).
 
UniProt ID:P70196
 
Species reactivity:Mouse
 
Applications:IP, WB
 
Recommended Dilutions/Conditions:Immunoprecipitation (2-4µL/100-500 µl cell extract from 5x106 cells)
Western Blot (1:1000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~58kDa by Western blot.
 
Purity Detail:Immunoaffinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:TRAF proteins are multifunctional signal adaptors that are involved in the activation of the kinase cascades which activate c-Jun N-terminal kinase, p38 mitogen activated protein kinase, and the transcription factor NF-κB. Members of the TRAF family form homodimers as well as heterodimers, resulting in extensive diversity and specificity to their function in signal transduction pathways.
 
TRAF6 polyclonal antibody Western blot
Western blot analysis of L5178Y (1), WR19L (2) and NIH/3T3 (3) cells, probed with TRAF6 pAb.
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TRAF6 polyclonal antibody Western blot

Product Literature References

A high-throughput pipeline for validation of antibodies: K. Sikorski, et al.; Nat. Methods 15, 909 (2018), Abstract;
The Nuclear Receptor AhR Controls Bone Homeostasis by Regulating Osteoclast Differentiation via the RANK/c-Fos Signaling Axis: T. Izawa, et al.; J. Immunol. 197, 4639 (2016), Abstract; Full Text

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