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TRAF2 polyclonal antibody

ADI-AAP-422-E 100 µl 301.00 USD
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Product Specification

Alternative Name:TNF receptor-associated factor 2
Immunogen:Recombinant mouse TRAF2 protein.
UniProt ID:P39429
Species reactivity:Human, Mouse
Recommended Dilutions/Conditions:Western Blot (1:1,000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~56kDa (mouse) or ~58kDa (human) by Western blot.
Purity Detail:Immunoaffinity purified.
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:TRAF proteins are multifunctional signal adaptors that are involved in the activation of the kinase cascades which activate c-Jun N-terminal kinase, p38 mitogen activated protein kinase, and the transcription factor NF-κB. Members of the TRAF family form homodimers as well as heterodimers, resulting in extensive diversity and specificity to their function in signal transduction pathways.
TRAF2 polyclonal antibody Western blot
Western blot analysis of HA-tag TRAF2 expressed cell lysate (1), and ZR75-1 (2), Raji (3), NIH3T3 (4), and WR19L12a (5) cell extracts, probed with TRAF2 pAb.
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TRAF2 polyclonal antibody Western blot

Product Literature References

A high-throughput pipeline for validation of antibodies: K. Sikorski, et al.; Nat. Methods 15, 909 (2018), Abstract;
The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death: E. Lafont, et al.; EMBO J. 36, 1147 (2017), Abstract; Full Text

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