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RAIDD polyclonal antibody

ADI-AAP-270-C 25 µg 136.00 USD
ADI-AAP-270-E 100 µg 282.00 USD
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Product Specification

Alternative Name:CRADD, Caspase and RIP adaptor with death domain, RIP-associated protein with a death domain
Immunogen:Synthetic peptide corresponding to a portion of human RAIDD.
UniProt ID:P78560
GenBank ID:U79115
Source:Purified from rabbit serum.
Species reactivity:Human, Rat
Hamster, Monkey
Applications:IHC, WB
Recommended Dilutions/Conditions:Immunohistochemistry (1:50)
Western Blot (1:500, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~24kDa by Western blot.
Purity Detail:Peptide affinity purified.
Formulation:Liquid. In borate buffered saline, pH 8.2, containing 25mM sodium borate, 100mM boric acid, 75mM sodium chloride, and 5mM EDTA (disodium salt).
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) also known as CRADD (caspase and RIP adapter with DD) contains a DD (death domain) and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNF-R1.
RAIDD polyclonal antibody Western blot
Western blot analysis of human K562 cell lysate, probed with RAIDD pAb
RAIDD polyclonal antibody Immunohistochemistry
Immunohistochemistry analysis of paraffin-embedded sections stained with RAIDD pAb. Peptide competition RAIDD is selectively increased in neurons in Alzheimer’s disease (right) in comparison to control (left).
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RAIDD polyclonal antibody Western blot RAIDD polyclonal antibody Immunohistochemistry

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