Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

DFF45/ICAD monoclonal antibody (6B8)

 
ADI-AAM-382-E 100 µg 320.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:CAD
 
Clone:6B8
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant human DFF45.
 
UniProt ID:O00273
 
Species reactivity:Human
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~45kDa (DFF45/ICAD-L) and ~40kDa (DFF45/ICAD-S) by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Lyophilized. In PBS, pH 7.2, containing 1% sucrose.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Human DNA fragmentation fragment (DFF) 45 and its mouse homologue caspase activated deoxyribonuclease (ICAD) are the inhibitors of DFF40 and CAD, respectively. DFF is composed of two subunits, DFF40/CAD and DFF45/ICAD. Cleavage of DFF45/ICAD, which is mediated by caspase-3, leads to DFF40/CADs activation as a nuclease. Activation of DFF40/CAD, which causes DNA degradation, is the hallmark of apoptotic cell death. DFF40 mRNA is expressed in a limited number of human tissues; pancreas, spleen, prostate, and ovary.
 
AAM-382 WB
Western blot analysis of Jurkat (1), Raji (2), A431 (3), MRC-5 (4), ZR- 75-1 (5), Hep-G2 (6), NIH/3T3 (7), WR19L (8), P19 (9) and PC12 (10) using DFF45/ICAD mAb (6B8).
Please mouse over
AAM-382 WB

Related Products

HeLa, (cell lysate) 

Human, WB | Print as PDF
 
ADI-LYC-HL100-F 200 µg 109.00 USD
Do you need bulk/larger quantities?
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
DFF
By biological activity:
DFF Monoclonal antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,