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BID monoclonal antibody (5C9)

 
ADI-AAM-141-E 100 µg 284.00 USD
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Product Specification

Alternative Name:BH3 interacting domain death agonist
 
Clone:5C9
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Synthetic peptide corresponding to a portion of human BID.
 
UniProt ID:P55957
 
Species reactivity:Human
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1-5µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~24kDa by Western blot.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:BID is an approximately 22 kDa protein belonging to the Bcl-2 family. BID is a cytosolic protein that is cleaved by caspase-8 in response to death receptor stimulation. Proteolytic cleavage of BID results in the formation of a 15 kDa fragment, referred to as tBID. tBID migrates to the mitochondria where it aids in the release of cytochrome c and the subsequent activation of the apoptosome. tBID serves as a link between death receptor dependent and mitochondrial mediated apoptosis.
 

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