- Biotin-free nanopolymer detection circumvents endogenous biotin background
- High intensity color development delivers sharp, crisp staining
- Customize with HIGHDEF® chromogens of your choice (sold separately)
The POLYVIEW® (mouse/rabbit-HRP) IHC detection reagent is a non-biotin one-step detection reagent suitable for demonstrating antigens in formalin-fixed paraffin-embedded tissues and frozen sections. The HRP detection reagent may also be used with blood smears, cytosmears, and cell preparations.
Product Details
| Applications: | IHC
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| Contents: | Anti-Mouse/Rabbit HRP detection reagent |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Technical Info/Product Notes: | POLYVIEW® IHC detection reagent (mouse/rabbit-HRP) has been developed by directly labeling anti-mouse and anti-rabbit immunoglobulins with enzymes using a proprietary tandem hyperlabelling technology. This ensures consistent and reproducible immunodetection of mouse and rabbit antibodies with a single reagent. Nuclear, cytoplasmic and membrane antigens in different types of tissues can be detected readily. The POLYVIEW® IHC detection reagent (mouse/rabbit-HRP) enables faster staining procedures than traditional two-step methods using biotin and avidin/streptavidin conjugates, with significantly lower background. The kit is suitable for use with all mouse and rabbit antibodies, both monoclonal and polyclonal. The reagents can be used for manual staining or with automated staining platforms. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
The differing pathophysiologies that underlie COVID-19-associated perniosis and thrombotic retiform purpura: a case series: C.M. Magro, et al.; Br. J. Dermatol.
184, 141 (2021),
Application(s): IHC on automated platform. Dermal samples.,
Abstract;
Full Text
Analysis of complement deposition and viral RNA in placentas of COVID-19 patients: J.J. Mulvey, et al.; Ann. Diagn. Pathol.
46, 151530 (2020),
Application(s): IHC on automated platform; human placenta (SARS-CoV-2 spike protein detection),
Abstract;
Full Text
Importin-β and exportin-5 are indicators of acute viral infection: Correlation of their detection with commercially available detection kits: G.J. Nuovo, et al.; Ann. Diagn. Pathol.
34, 36 (2018),
Application(s): Comparison with Leica HRP. IHC on: infected brain tissues with rabies virus; mice infected with acute reovirus infection; CIN, Herpes simplex virus and molloscum contagiosum lesions,
Abstract;
Increased expression of importin-β, exportin-5 and nuclear transportable proteins in Alzheimer's disease aids anatomic pathologists in its diagnosis: G. Nuovo, et al.; Ann. Diag. Pathol.
32, 10 (2018),
Application(s): Immunohistochemistry on human brain FFPE tissue,
Abstract;
New biomarkers of human papillomavirus infection in acute cervical intraepithelial neoplasia: G.J. Nuovo, et al.; Ann. Diagn. Pathol.
36, 21 (2018),
Abstract;
Widespread extrahepatic expression of acute-phase proteins in healthy chicken (Gallus gallus) tissues: A.T. Marques, et al.; Vet. Immunol. Immunopathol.
190, 10 (2017),
Abstract;
Expression of α1-acid glycoprotein and lipopolysaccharide binding protein in visceral and subcutaneous adipose tissue of dairy cattle: M.M. Rahman, et al.; Vet. J.
203, 223 (2015),
Application(s): Immunohistochemistry on frozen sections,
Abstract;
The localization and differential expression of Serum Amyloid A in bovine liver and adipose tissue depots: F. Ceciliani, et al.; Vet. Immunol. Immunopathol.
168, 35 (2015),
Application(s): IHC using frozen tissue,
Abstract;
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