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PIP monoclonal antibody

 
ADI-915-045-500 0.5 ml 269.00 USD
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Product Specification

Alternative Name:Phosphatidylinositol-4 monophosphate
 
Clone:not available
 
Host:Mouse
 
Isotype:IgM
 
Immunogen:Native PIP from bovine spinal cord.
 
Species reactivity:Species independent
 
Applications:ELISA, ICC
Radioimmunoassay
 
Formulation:Liquid. Ascites.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Metabolism of inositol phospholipids by intracellular signaling mediators is fundamental to signal transduction in eukaryotic cells. PI-4,5-P2 (PIP2) can be synthesized by phosphorylation of PI-4-P by type I phosphatidylinositol phosphate kinase (PIP5K I), or phosphorylation of PI-5-P by type II PIPK (PIP4K II). PI-4,5-P2 regulation of cellular calcium levels involves its hydrolysis by Phospholipase C (PLC) to produce inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG), which serve as second messengers in the import of calcium via IP3-sensitive ion channels and in the activation of PKC, respectively.
 

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