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CD23 (human), (recombinant)

ADI-908-246-010 10 µg 346.00 USD
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Product Specification

MW:~48kDa (including GST-tag)
Source:Produced in E. coli. Recombinant human CD23 (aa 48-248).
UniProt ID:P06734
Formulation:Liquid. In 50mM TRIS-Acetate, pH 7.5, containing 1mM EDTA and 20% glycerol. Does not contain BSA or sodium azide.
Purity:≥80% (SDS-PAGE)
Purity Detail:Purified by glutathione sepharose.
Applications:ELISA, WB
Inhibition assay
Application Notes:Western blot control.
Shipping:Shipped on Dry Ice
Long Term Storage:-80°C
Scientific Background:The cluster of differentiation (CD) proteins are a group of surface molecules so named for their use in the identification and classification of leukocytes. The structure and function of CD proteins varies greatly and includes a multitude of receptors involved in cell adhesion, signal transduction, and antigen recognition. For example, CD8 (cytotoxic) and CD8 (helper) are well established T-lymphocyte markers, and function as co-receptors for MHC-I and MHC-II, respectively. CD23 is a 45 kDa glycoprotein present on a subpopulation of freshly isolated peripheral blood and tonsil B cells, and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 occurs in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some cases of centroblastic/centrocytic lymphoma.

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