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GM-CSF (mouse), (recombinant)

ADI-908-064-005 5 µg 170.00 USD
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Product Specification

Alternative Name:CSF2, Colony stimulating factor 2 (granulocyte-macrophage)
Source:Produced in E. coli.
UniProt ID:P01587
Formulation:Lyophilized. 2 μg of sterile filtered liquid lyophilized after extensive dialysis against 10 mM acetic acid buffer; very soluble in water and most aqueous buffers. It is recommended to reconstitute this protein in sterile 20mM AcOH (acetic Acid) not less than 100mg/ml.
Purity:≥99% (RP-HPLC; Anion-exchange FPLC; Reducing and non-reducing SDS-PAGE)
Purity Detail:Purified by multi-step chromatography.
Endotoxin Content:<0.1ng/µg (IEU/µg purified protein (LAL test))
Applications:in vitro Assay
Shipping:Shipped on Dry Ice
Long Term Storage:+4°C
Scientific Background:The cytokine Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) controls the production, differentiation, and function of granulocytes and macrophages. The active form of GM-CSF functions extracellularly as a homodimer. Localized to a cluster of related genes at chromosome region 5q31 , data links this gene to interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

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