Acetyltransferase activity kit



ADI-907-026	96 wells	385.00 USD

Universal - suitable for any AcetylCoA-dependent acetyltransferase
Robust - Z' factor = 0.87
Sensitive - fluorescent detection allows for both DNA and protein assays
Higher throughput - homogeneous mix-and-read assay

The Acetyltransferase activity kit is a homogeneous mix-and-read fluorescent assay for the determination of any acetyl-CoA dependent acetyltransferase activity. It is suitable for end-point or kinetic read options, which is ideal for determining mechanism of action, kinetics, and screening candidate compounds. The assay is amendable to HTS and miniaturization.

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Product Specification

Kit/Set Contains:	Black Microtiter plate, Reaction buffer, Assay buffer, Detection solution, Positive control

Application:	For the measurement of acetyl-CoA dependent acetyltransferase activity in purified in vitro samples that do not contain reductants from any species.

Use/Stability:	Store all components at -20°, except assay buffer at +4° and positive control at -80°.

Miscellaneous/General:	Acetylation of proteins and drugs is a regulatory event that can result in the activation, inactivation, or detoxification of molecules including histones, kinases, transcription factors, anti-microbial agents, and neurotransmitters. While acetylation can be carried out by a variety of acetyltransferase enzymes using diverse substrates, their common cofactor or acetyl donor is acetyl-CoA.