Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

COX activity kit

 
ADI-907-003 96 wells 381.00 USD
Do you need bulk/larger quantities?
 
  • Fast - results in less than 2 hours from up to 40 samples in duplicate
  • Flexible - evaluate COX-1 and/or COX-2 inhibitors
  • Precise - intra-assay variation < 7%
The COX activity kit is the first commercially available non-radioactive COX activity assay. This kit lets you easily evaluate COX I and COX II inhibitors in a convenient 96-well plate based assay with < 7% intra-assay variation.
907-003-Kit-Graph
Please mouse over
907-003-Kit-Graph

Product Specification

Alternative Name:Cyclooxygenase, Prostaglandin H synthase
 
Sensitivity:0.147 Units/ml COX-I (range 7.5 - 60 Units/ml)
 
Applications:Chemiluminescence
Activity assay
 
Application Notes:For the measurement of COX-1 and COX-2 activity.
 
Use/Stability:Store all components at +4°, except Inhibitors at -20°.
 
Shipping:Shipped on Blue Ice
 
Kit/Set Contains:Microtiter plate, Chemiluminescent substrate, Ibuprofen, Meloxicam
 
Scientific Background:Cyclooxygenases-1 and 2 (COX-1 and COX-2) also known as Prostaglandin endoperoxide H synthases-1 and 2 are integral membrane proteins which catalyze the first step of prostaglandin, thromboxane, and prostacyclin production from arachidonic acid. The COX-1 and COX-2 enzymes are important pharmacologically as targets of nonsteroidal anti-inflammatory drugs (NSAIDs) including aspirin, ibuprofen and the COX-2 inhibitors. Inhibition of cyclooxygenases with NSAIDs acutely reduces inflammation, pain, and fever.
 
UniProt ID:P23219 (COX-1), P35354 (COX-2)
 

Product Literature References

Insight into the molecular mechanism of an herbal injection by integrating network pharmacology and in vitro: Y.M. Ma, et al.; J. Ethnopharmacol. 173, 91 (2015), Application(s): Chemiluminescence, Abstract;

Related Products

PLAQPRO® Lp-PLA2 Assay 

Enzyme activity kit to measure Lp-PLA2 activity in  serum samples
Colorimetric detection, HTS | Print as PDF
 
ENZ-KIT179-0200 200 tests Inquire for pricing
Do you need bulk/larger quantities?
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis
Manual

RELATED PRODUCTS

By target:
COX
By biological activity:
COX Activity kit
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Brochures
Integrated solutions for screening Wnt regulators
Integrated solutions for screening Wnt regulators
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,