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KIM-1 (human) monoclonal antibody (3F4)

 
ADI-905-906-0100 100 µg 378.00 USD
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Product Specification

Alternative Name:Kidney Injury Molecule-1, HAVcr-1, TIMD-1, TIM-1
 
Clone:3F4
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant human KIM-1.
 
UniProt ID:Q96D42.2
 
Species reactivity:Human
 
Applications:ELISA, Flow Cytometry, WB
 
Purity Detail:Protein G-affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Kidney Injury Molecule-1 (KIM-1) is a type 1 transmembrane protein, with an immunoglobulin and mucin domain, whose expression is markedly up-regulated in the proximal tubule in the post-ischemic rat kidney. KIM-1 is a potential biomarker for renal injury or renal inflammation.  It is a traditional blood and urine marker for the diagnosis of various renal diseases.
 
ADI-905-906 WB
Western blot analysis of KIM-1 (human), mAb (3F4) (Prod. No. ADI-905-906): Lane 1: MW marker, Lane 2: HeLa, (cell lysate) (Prod. No. ADI-LYC-HL100), Lane 3: CaKi-2 (cell lysate).
ADI-905-906 flow
Flow cytometry analysis of 106 CaKi-2 cells stained using KIM-1 (human), mAb (3F4), FITC Conjugate at concentrations of 25µg/ml and 5µg/ml.
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ADI-905-906 WB ADI-905-906 flow

General Literature References

Application of emerging biomarkers of acute kidney injury in development of kidney-sparing polypeptide-based antibiotics: D. Burt, et al.; Drug Chem. Toxicol. 37, 204 (2014), Abstract;

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ADI-905-905-0100 100 µg 378.00 USD
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