Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

LTC4 monoclonal antibody (6E7)

 
ADI-905-902-0050 50 µg 205.00 USD
 
ADI-905-902-0200 200 µg 420.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:Leukotriene C4
 
Clone:6E7
 
Host:Mouse
 
Isotype:IgG
 
Immunogen:Leukotriene C4
 
Source:Purified from concentrated hybridoma tissue culture supernatant.
 
Species reactivity:Human, Mouse, Rat
 
Applications:ELISA
Radioimmunoassay
 
Recommended Dilutions/Conditions:Radioimmunoassay (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Leukotrienes are metabolic products of arachidonic acid formed by the action of 5-lipoxygenase (5-LO), with the principal products being leukotrienes C4 (LTC4) and B4 (LTB4). Leukotriene B4 (LTB4) stimulates leukocyte functions including lysosomal enzyme release, adhesion, and aggregation of polymorphonuclear leukocytes. LTB4 has been implicated as a potent mediator of inflammatory diseases and immunoregulation. The cysteinyl leukotrienes (LTC4, LTD4, and LTE4) are formed by addition of cysteine derivatives to LTA4. The conversion of LTA4 to LTC4 by the enzyme LTC4 synthase limits the rate of cysteinyl leukotriene formation. Cysteinyl leukotrienes are potent lipid mediators in inflammation, inducing smooth muscle contractions and increased capillary permeability.
 

General Literature References

International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors: C. Brink, et al.; Pharmacol. Rev. 55, 195 (2003), Abstract;
Leukotriene B4: metabolism and signal transduction: T. Yokomizo, et al.; Arch. Biochem. Biophys. 385, 231 (2001), Abstract;

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
Leukotriene synthase
By biological activity:
Leukotriene synthase Monoclonal antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,