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VEGF A monoclonal antibody (4G3)

 
ADI-905-861-100 100 µl 410.00 USD
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Product Specification

Alternative Name:Vascular endothelial growth factor A
 
Clone:4G3
 
Host:Mouse
 
Isotype:IgG2b
 
Immunogen:Recombinant human VEGF (aa 27-233).
 
UniProt ID:P15692
 
Species reactivity:Human
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1:5,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~21kDa (full length), dimers observed by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:VEGF is a member of the PDGF/VEGF growth factor family that is often found as a disulfide linked homodimer. It is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGF gene have been associated with proliferative and nonproliferative diabetic retinopathy.
 
905-861 WB
Western blot analysis: Recombinant Human VEGF165 probed with VEGF mAb (4G3) at 1:5000.
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905-861 WB

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