BMP4, mAb (6B7)

Alternative Name:	bone morphogenetic protein

Purity Detail:	Protein G affinity purified.

Formulation:	Liquid. In PBS, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Clone:	6B7

Isotype:	Mouse IgG1

Immunogen:	Recombinant human BMP4 (aa 293-408).

Specificity:	Recognizes human BMP4. Detects a band of ~47kDa (full length) by Western blot.

Application:	Western Blot (1:100,000) Optimal conditions must be determined individually for each application.

Long Term Storage:	-20°C

Miscellaneous/General:	BMP4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva.