Akt3, mAb (9B2)

Alternative Name:	PKB, Protein kinase B, RAC

Purity Detail:	Protein G affinity purified.

Formulation:	Liquid. In PBS, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Clone:	9B2

Isotype:	Mouse IgG3

Immunogen:	Recombinant human Akt3 (aa 2-479).

Specificity:	Recognizes human and mouse Akt3. Detects a band of ~54kDa (full length) by Western blot.

Application:	Western Blot (1:500) Optimal conditions must be determined individually for each application.

Long Term Storage:	-20°C

Miscellaneous/General:	AKT3 is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).