Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

LTB4 receptor (BLT1) polyclonal antibody

ADI-905-793-100 100 µg 296.00 USD
Do you need bulk/larger quantities?

Product Specification

Alternative Name:Leukotriene B4 Receptor 1, LTB4-R1
Immunogen:Synthetic peptide corresponding to the sequence near the N-terminus of rat LTB4 Receptor (BLT1).
UniProt ID:Q9R0Q2
Species reactivity:Rat
Crossreactivity:Predicted species reactivity based on epitope sequence homology: mouse.
Application Notes:Predicted MW of ~38kDa. Higher MW species (~50kDa) also observed by Western blot which reflect post-translational modification of the receptor.
Purity Detail:Peptide affinity purified.
Formulation:Liquid. In PBS containing 50% glycerol and 0.01% sodium azide.
Handling:Keep on ice at all times.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:Leukotrienes are metabolic products of arachidonic acid formed by the action of 5-lipoxygenase (5-LO), with the principal products being leukotrienes C4 (LTC4) and B4 (LTB4). LTB4 is a dihydroxy-leukotriene produced in a variety of cells including eosinophils, neutrophils, platelets, and vascular cells, and is a potent leukocyte chemoattractant known to regulate leukocyte activation, cytokine secretion, inflammatory gene transcription, and IgE synthesis. As such, LTB4 has been implicated in a number of disease pathologies including atherosclerosis, asthma, psoriasis, and inflammatory bowel disease. The many actions of LTB4 are associated with two identified mammalian receptors, BLT1 and BLT2. BLT1 is a high-affinity LTB4 receptor expressed on peripheral leukocytes, while BLT2 is a more ubiquitously expressed low affinity LTB4 receptor whose function is not well understood. The BLT1 receptor is transiently expressed by antigen-primed T-cells in humans, and its expression is known to play a critical role in collagen-induced arthritis in mice.
Manufacturer:Manufactured by Proteimax.
LTB4 receptor (BLT1) polyclonal antibody Western blot
Western blot analysis: MW marker (1) and 50µg rat heart membrane extract (2) probed with LTB4 Receptor (BLT1) pAb at 4.9µg/ml.
Please mouse over
LTB4 receptor (BLT1) polyclonal antibody Western blot

Product Literature References

Generation of G protein-coupled receptor antibodies differentially sensitive to conformational states: A.S. Heimann, et al.; PloS One 12, e0187306 (2017), Abstract; Full Text

Related Products

Goat anti-rabbit IgG, polyclonal antibody (HRP conjugate) 

ELISA, IHC, WB | Print as PDF
ADI-SAB-300-J 1 ml 124.00 USD
Do you need bulk/larger quantities?

Related Literature

Technical Posters
Arachidonic Acid Metabolites
Arachidonic Acid Metabolites
Download as PDF

All new literature pieces

Recommend this page

For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2019 Enzo Life Sciences, Inc.,