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Cdk1/cdc2 monoclonal antibody (POH1)

 
ADI-905-777-100 100 µg 248.00 USD
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Product Specification

Alternative Name:Cyclin-dependent kinase 1, p34cdc2, Cell division cycle 2
 
Clone:POH1
 
Host:Mouse
 
Immunogen:Recombinant full length human Cdk1/cdc2.
 
UniProt ID:P06493
 
Species reactivity:Human
 
Applications:IHC (PS), WB
 
Recommended Dilutions/Conditions:Western Blot (1µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:The cell division cycle (cdc) group of proteins consists of many protein classes, including cyclin dependent kinases (Cdks), phosphoprotein phosphatases, mitogen activated kinases, small GTPases, and cyclins. These proteins play a central role in regulating progression through the cell cycle through the formation and/or modification of key substrates. Cdc42 belongs to the Rho-family of GTPases, and promotes actin polymerization to form filopodia. Cdc25A is a dual-specificity phosphatase that acts on phosphorylated threonine and tyrosine residues of Cdks, leading to binding and activation of their partner cyclins.
 
905-777 WB
Western blot analysis of cdc2. Lane 1: MW, Lane 2: HeLa.
ADI-905-777 IHC
IHC Analysis: Human thymus tissue stained with Cdk1/cdc2, mAb (POH1) at 20µg/ml.
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905-777 WB ADI-905-777 IHC

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