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Cyclin D1 monoclonal antibody (DCS6)

 
ADI-905-776-100 100 µg 269.00 USD
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Replaces Prod. #: ALX-804-001

Product Specification

Alternative Name:CCND1
 
Clone:DCS6
 
Host:Mouse
 
Immunogen:Recombinant full length human Cyclin D1.
 
UniProt ID:P24385
 
Species reactivity:Human, Mouse, Rat
 
Applications:WB
 
Recommended Dilutions/Conditions:Western Blot (1µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~36kDa by Western blot.
 
Purity Detail:Protein G affinity purified.
 
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Cyclins are a family of proteins which function as the regulatory subunits of cyclin/cyclin-dependent kinase (Cdk) holoenzymes, mediating entry into and progression through the cell cycle. Each cyclin is expressed in a temporal fashion during the cell cycle, partnering with a specific Cdk to activate its protein kinase activity. The most well defined mitotic cyclins are: cyclin D, which partners with cdks 4 and 6 during early G1 phase; cyclin E, which activates Cdk2 in the G1 to S phase transition; cyclin A, which utilizes Cdks 1 and 2 during progression through S phase and into G2; and cyclin B, which activates Cdk1 in M-phase promotion.
 
905-776 WB
Western blot analysis of Cyclin D1. Lane 1: MW, Lane 2: 3T3, Lane 3: L929, Lane 4: PC-12, Lane 5: A431.
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905-776 WB

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